Effect of live Salmonella Ty21a in Dextran Sulfate Sodium-induced Colitis | Zendy

Gunnar Nysœter | Zendy; Kari Erichsen | Zendy; Anne Marita Milde | Zendy; Eva Colás | Zendy; E. K. Kristoffersen | Zendy; Arnold Berstad | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Effect of live Salmonella Ty21a in Dextran Sulfate Sodium-induced Colitis

Author(s) -

Gunnar Nysœter,

Kari Erichsen,

Anne Marita Milde,

Eva Colás,

E. K. Kristoffersen,

Arnold Berstad

Publication year - 2007

Publication title -

drug target insights

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.297

H-Index - 12

ISSN - 1177-3928

DOI - 10.4137/dti.s220

Subject(s) - medicine , salmonella , salmonella typhi , inflammatory bowel disease , colitis , salmonella enterica , salmonella infection , gastroenterology , immunology , disease , bacteria , biology , escherichia coli , biochemistry , genetics , gene

Intestinal microbiota seems to play an essential role in the development of inflammatory bowel diseases (IBD). We hypothesised that an oral vaccine based on live Salmonella typhi would be well tolerated and could even attenuate dextran sulfate sodium (DSS) induced colitis in rats, an animal model of IBD.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research