Comparison of the Blood and Lymphatic Microvessel Density of Pleomorphic Adenoma and Basal Cell Adenoma
Author(s) -
Andresa Borges Soares,
Albina Alternarli,
Thais Ribeiro De Oliveira,
Felipe de Oliveira Fonseca Rodrigues,
Alfredo RibeiroSilva,
Danilo Figueiredo Soave,
Fabrício PassadorSantos,
Suéllen Trentin Brum,
Marcelo Henrique Napimoga,
Vera Cavalcanti de Araújo
Publication year - 2015
Publication title -
clinical medicine insights pathology
Language(s) - English
Resource type - Journals
ISSN - 1179-5557
DOI - 10.4137/cpath.s23035
Subject(s) - lymphatic system , cd34 , pathology , lymphatic vessel , microvessel , adenoma , blood vessel , vascular endothelial growth factor , vascularity , endoglin , pleomorphic adenoma , medicine , biology , immunohistochemistry , salivary gland , vegf receptors , cancer , stem cell , metastasis , genetics
Pleomorphic adenoma (PA) is the most common tumor of the salivary gland, while basal cell adenoma (BCA) is an uncommon neoplasm. Blood and lymphatic vessels are crucial for tumor metabolism. The aim of this study was to compare the blood and lymphatic vascular density and vascular and endothelial growth factor (VEGF) expression in PA and BCA tumors. In addition, cell proliferation was evaluated in these tumors.
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