A practical Guide to Treatment with Liraglutide

Liraglutide—a once-daily human glucagon-like peptide-1 receptor agonist for treatment of Type 2 diabetes—provides effec- tive glycemic control with a lower incidence of hypoglycemia than therapies such as glimepiride and exenatide, and reduces body weight and systolic blood pressure. This article briefly discusses efficacy and safety results from the Liraglutide Effect and Action in Diabetes (LEAD) program, before considering practical issues of identifying and educating patients who may be suitable for liraglutide therapy.