Emerging Pharmacotherapies for Adult Patients with Acute Lymphoblastic Leukemia | Zendy

Lydia Lee | Zendy; Adele K. Fielding | Zendy

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Emerging Pharmacotherapies for Adult Patients with Acute Lymphoblastic Leukemia

Author(s) -

Lydia Lee,

Adele K. Fielding

Publication year - 2012

Publication title -

clinical medicine insights oncology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.601

H-Index - 26

ISSN - 1179-5549

DOI - 10.4137/cmo.s7262

Subject(s) - medicine , lymphoblastic leukemia , intensive care medicine , oncology , salvage therapy , disease , complete remission , leukemia , chemotherapy

Acute lymphoblastic leukemia (ALL) treatment regimes are amongst the longest, most intensive and complex used in hematooncology. Despite this, while treatment of pediatric ALL is a success story, we are far from being able to ensure a durable response in adult ALL. This is not due to failure of induction therapy as a complete remission (CR) is achieved in over 90% of patients. However the challenge remains in ensuring a sustained remission. Furthermore in the face of relapsed disease, salvage therapies currently offer a poor chance of a good outcome. This article reviews the novel agents which show the most promise in the treatment of adult ALL.

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