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also reported a positive experience in liver metastases from non-neuroendocrine tumors with the use of octreotide LAR.A possible antitumor mechanism of octreotide is a stimulatory effect on Kupffer cells, induction of apoptosis or other antiproliferative actions, inhibition of proliferation, which have been suggested but not proved.

Octreotide in Palliative Treatment of Unresectable Cholangiocarcinoma: Is it Effective for Disease Stabilization?