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Long-Term Treatment of Metastatic Colorectal Cancer with Panitumumab
Author(s) -
Miriam López-Gómez,
Maria J. Merino,
Enrique Casado
Publication year - 2012
Publication title -
clinical medicine insights oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.601
H-Index - 26
ISSN - 1179-5549
DOI - 10.4137/cmo.s5055
Subject(s) - panitumumab , colorectal cancer , medicine , oncology , monoclonal antibody , chemotherapy , disease , cancer , cetuximab , antibody , immunology
Colorectal cancer is one of the leading causes of cancer-related deaths worldwide. More than 30% patients present with metastases at diagnoses and will require systemic chemotherapy. In recent years many anti-EGFR targets have been developed. Among them, panitumumab, a fully human IgG2 monoclonal antibody has shown important benefits in the treatment of this disease.

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