Open AccessMelatonin, a Promising Role in Taxane-Related Neuropathy
Author(s) -
Zeihleh,
Jane M. Pruemer,
Jennifer Ann LaFollette,
S. Sweany
Publication year - 2010
Publication title -
clinical medicine insights oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.601
H-Index - 26
ISSN - 1179-5549
DOI - 10.4137/cmo.s4132
Subject(s) - taxane , medicine , melatonin , docetaxel , peripheral neuropathy , chemotherapy , oncology , chemotherapy induced peripheral neuropathy , adverse effect , breast cancer , cancer , endocrinology , diabetes mellitus
Melatonin has neuroprotective effects in animal studies and has been suggested to decrease adverse reactions of chemotherapy including neuropathy. This pilot trial aimed at assessing whether melatonin, given during taxane chemotherapy for breast cancer, will decrease the incidence and/or severity of neuropathy.
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