Open AccessSuccessful Downstaging of High Rectal and Recto-Sigmoid Cancer by Neo-Adjuvant Chemo-Radiotherapy
Author(s) -
Brian O′Neill,
Gina Brown,
Andrew Wotherspoon,
Sarah Burton,
Andy Norman,
Diana Tait
Publication year - 2008
Publication title -
clinical medicine oncology
Language(s) - English
Resource type - Journals
ISSN - 1177-9314
DOI - 10.4137/cmo.s348
Subject(s) - medicine , oxaliplatin , rectum , chemoradiotherapy , radiation therapy , surgery , colorectal cancer , stage (stratigraphy) , chemotherapy , radiology , cancer , paleontology , biology
The benefit of neoadjuvant therapy for tumours above the peritoneal reflection is not clear. The purpose of this study is to demonstrate the feasibility and downstaging of treating locally advanced tumours from high rectum to distal sigmoid with preoperative chemoradiotherapy (CRT).
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