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Acute Visual Loss Induced by Dexamethasone during Neoadjuvant Docetaxol
Author(s) -
D. Gregory,
Colin D. Jones,
E Denton,
A.N. Harnett
Publication year - 2008
Publication title -
clinical medicine oncology
Language(s) - English
Resource type - Journals
ISSN - 1177-9314
DOI - 10.4137/cmo.s339
Subject(s) - medicine , serous fluid , retinopathy , dexamethasone , chemotherapy , regimen , visual acuity , premedication , presentation (obstetrics) , surgery , endocrinology , diabetes mellitus
We present a case of a female patient who developed acute onset of visual loss due to central serous retinopathy as a consequence of steroid premedication for docetaxol given as second line neoadjuvant chemotherapy for breast cancer. Central serous retinopathy is a recognised association with steroids but has not been previously reported in association with the management of solid tumours. Reduction in steroid dose and duration permitted recovery of her visual acuity while allowing completion of the prescribed chemotherapy regimen. An overview of the presentation, pathogenesis, aetiologies and management of central serous retinopathy is given.

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