Development of Interpretable Predictive Models for BPH and Prostate Cancer
Author(s) -
Pablo Bermejo,
Alicia Vivo,
Pedro Juan Tárraga,
José Antonio RodríguezMontes
Publication year - 2015
Publication title -
clinical medicine insights oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.601
H-Index - 26
ISSN - 1179-5549
DOI - 10.4137/cmo.s19739
Subject(s) - prostate cancer , medicine , prostate , logistic regression , rectal examination , predictive value , urology , prostate biopsy , hyperplasia , prostate specific antigen , receiver operating characteristic , oncology , cancer
Traditional methods for deciding whether to recommend a patient for a prostate biopsy are based on cut-off levels of stand-alone markers such as prostate-specific antigen (PSA) or any of its derivatives. However, in the last decade we have seen the increasing use of predictive models that combine, in a non-linear manner, several predictives that are better able to predict prostate cancer (PC), but these fail to help the clinician to distinguish between PC and benign prostate hyperplasia (BPH) patients. We construct two new models that are capable of predicting both PC and BPH.
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