Difference between Luminal A and Luminal B Subtypes According to Ki-67, Tumor Size, and Progesterone Receptor Negativity Providing Prognostic Information
Author(s) -
Zorka Inić,
Milan Žegarac,
M. Inić,
Ivan Marković,
Zoran Kozomara,
Igor Djurisic,
Ivana Inić,
Gordana Pupić,
Snežana Jančić
Publication year - 2014
Publication title -
clinical medicine insights oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.601
H-Index - 26
ISSN - 1179-5549
DOI - 10.4137/cmo.s18006
Subject(s) - negativity effect , progesterone receptor , medicine , receptor , oncology , biology , psychology , cancer , developmental psychology , estrogen receptor , breast cancer
The St. Gallen International Expert Consensus of 2011 proposes a new classification system for breast cancer based on its division into five subgroups. The criteria to identify these subtypes were recently refined at the 2013 Conference. In this respect, the authors of this paper have conducted a retrospective analysis of breast cancer subtypes, related to Ki-67 and involvement of the axillary lymph nodes (ALNs). The analysis was performed only in the cases of invasive breast cancer in the pT2 stages. The research and results of the paper have shown that investigating the value of these parameters could be of great benefit in future treatment strategies of invasive breast cancer.
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