No Postoperative Adrenal Insufficiency in a Patient with Unilateral Cortisol-Secreting Adenomas Treated with Mifepristone before Surgery | Zendy

Rachel M. Saroka | Zendy; Michael P. Kane | Zendy; Lawrence R. Robinson | Zendy; Robert S. Busch | Zendy

Open Access

No Postoperative Adrenal Insufficiency in a Patient with Unilateral Cortisol-Secreting Adenomas Treated with Mifepristone before Surgery

Author(s) -

Rachel M. Saroka,

Michael P. Kane,

Lawrence R. Robinson,

Robert S. Busch

Publication year - 2016

Publication title -

clinical medicine insights endocrinology and diabetes

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.527

H-Index - 15

ISSN - 1179-5514

DOI - 10.4137/cmed.s39997

Subject(s) - medicine , mifepristone , adrenal insufficiency , diabetes mellitus , adrenocorticotropic hormone , glucocorticoid , endocrinology , dexamethasone , dehydroepiandrosterone sulfate , surgery , adrenal gland , gastroenterology , hormone , androgen , pregnancy , genetics , biology

Glucocorticoid replacement is commonly required to treat secondary adrenal insufficiency after surgical resection of unilateral cortisol-secreting adrenocortical adenomas. Here, we describe a patient with unilateral cortisol-secreting adenomas in which the preoperative use of mifepristone therapy was associated with recovery of the hypothalamic-pituitary-adrenal (HPA) axis, eliminating the need for postoperative glucocorticoid replacement.

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