Age and Menopausal Status Affect Osteoprotegerin and Osteocalcin Levels in Women Differently, Irrespective of Thyroid Function
Author(s) -
Alexander Shinkov,
Anna-Maria I. Borissova,
Roussanka Кovatcheva,
lliana B. Atanassova,
Jordan Vlahov,
Lilia Dakovska
Publication year - 2014
Publication title -
clinical medicine insights endocrinology and diabetes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.527
H-Index - 15
ISSN - 1179-5514
DOI - 10.4137/cmed.s15466
Subject(s) - medicine , endocrinology , euthyroid , osteoprotegerin , osteocalcin , menopause , body mass index , thyroid function , bone remodeling , hormone , thyroid , chemistry , alkaline phosphatase , biochemistry , receptor , activator (genetics) , enzyme
Osteoprotegerin (OPG) and osteocalcin (OC) are essential bone proteins. Recent studies have demonstrated that they are not secreted solely by bone cells; they play roles in the vascular function and energy metabolism, and they are influenced by multiple factors. The aim of the current study was to investigate the influence of menopause and age on OPG and OC in women with different thyroid-stimulating hormone (TSH) levels.
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