Simultaneous Treatment with Subcutaneous Injection of Golimumab and Intra-articular Injection of Triamcinolone Acetonide (K-Method) in Patients with Rheumatoid Arthritis Undergoing Switching of Biologics: Retrospective Case–Control Study | Zendy

Katsuaki Kanbe | Zendy; Junji Chiba | Zendy; Yasuo Inoue | Zendy; Masashi Taguchi | Zendy; Akiko Yabuki | Zendy; Tomohiko Deguchi | Zendy

Open Access

Simultaneous Treatment with Subcutaneous Injection of Golimumab and Intra-articular Injection of Triamcinolone Acetonide (K-Method) in Patients with Rheumatoid Arthritis Undergoing Switching of Biologics: Retrospective Case–Control Study

Author(s) -

Katsuaki Kanbe,

Junji Chiba,

Yasuo Inoue,

Masashi Taguchi,

Akiko Yabuki,

Tomohiko Deguchi

Publication year - 2016

Publication title -

clinical medicine insights arthritis and musculoskeletal disorders

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.418

H-Index - 21

ISSN - 1179-5441

DOI - 10.4137/cmamd.s38442

Subject(s) - medicine , golimumab , triamcinolone acetonide , rheumatoid arthritis , lidocaine , visual analogue scale , rheumatism , etanercept , retrospective cohort study , surgery , acetonide , arthritis

Tight control of severe rheumatoid arthritis (RA) in patients with high disease activity, even when using biologics, is sometimes difficult using a treat-to-target strategy. Switching from one biologic to another is associated with lower efficacy than that in treatment-naive cases. We developed the K-method that involves simultaneous treatment with golimumab and intra-articular joint injection of triamcinolone acetonide (TA) in patients undergoing switching of biologics. We performed this retrospective case-control study to investigate the efficacy of achieving an immediate treatment response using the K-method.

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