An Integrative Analysis of microRNA and mRNA Expression–-A Case Study
Author(s) -
LiXuan Qin
Publication year - 2008
Publication title -
cancer informatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.606
H-Index - 31
ISSN - 1176-9351
DOI - 10.4137/cin.s633
Subject(s) - microrna , hierarchical clustering , computational biology , gene expression , cluster analysis , biology , gene , gene expression profiling , regulation of gene expression , gene regulatory network , dna microarray , bioinformatics , genetics , computer science , artificial intelligence
MicroRNAs are believed to play an important role in gene expression regulation. They have been shown to be involved in cell cycle regulation and cancer. MicroRNA expression profiling became available owing to recent technology advancement. In some studies, both microRNA expression and mRNA expression are measured, which allows an integrated analysis of microRNA and mRNA expression.
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