Genes with Relevance for Early to Late Progression of Colon Carcinoma Based on Combined Genomic and Transcriptomic Information from the Same Patients
Author(s) -
Kristina K. Lagerstedt,
Erik Kristiansson,
Christina Lönnroth,
Marianne Andersson,
BrittMarie Iresjö,
Annika Gustafsson,
Elisabeth Hansson,
Ulf Kressner,
S. Nordgren,
Fredrik Enlund,
Kent Lundholm
Publication year - 2010
Publication title -
cancer informatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.606
H-Index - 31
ISSN - 1176-9351
DOI - 10.4137/cin.s4545
Subject(s) - biology , microrna , colorectal cancer , gene , tumor progression , comparative genomic hybridization , transcriptome , epigenetics , gene expression , cancer research , cancer , chromosome , genetics
Genetic and epigenetic alterations in colorectal cancer are numerous. However, it is difficult to judge whether such changes are primary or secondary to the appearance and progression of tumors. Therefore, the aim of the present study was to identify altered DNA regions with significant covariation to transcription alterations along colon cancer progression.
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