Effect of Quantitative Nuclear Image Features on Recurrence of Ductal Carcinoma In Situ (DCIS) of the Breast
Author(s) -
David Axelrod,
Naomi Miller,
H. Lavina A. Lickley,
Jin Qian,
William A. ChristensBarry,
Yan Yuan,
Yuejiao Fu,
JudithAnne W. Chapman
Publication year - 2008
Publication title -
cancer informatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.606
H-Index - 31
ISSN - 1176-9351
DOI - 10.4137/cin.s401
Subject(s) - grading (engineering) , medicine , ductal carcinoma , nuclear medicine , radiology , breast cancer , cancer , civil engineering , engineering
Nuclear grade has been associated with breast DCIS recurrence and progression to invasive carcinoma; however, our previous study of a cohort of patients with breast DCIS did not find such an association with outcome. Fifty percent of patients had heterogeneous DCIS with more than one nuclear grade. The aim of the current study was to investigate the effect of quantitative nuclear features assessed with digital image analysis on ipsilateral DCIS recurrence.
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