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Computing Molecular Signatures as Optima of a Bi-Objective Function: Method and Application to Prediction in Oncogenomics
Author(s) -
Vincent Gardeux,
Rachid Chelouah,
Maria Fernanda Barbosa Wanderley,
Patrick Siarry,
Antônio P. Braga,
Fabien Reyal,
Roman Rouzier,
Lajos Pusztai,
René Natowicz
Publication year - 2015
Publication title -
cancer informatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.606
H-Index - 31
ISSN - 1176-9351
DOI - 10.4137/cin.s21111
Subject(s) - feature selection , computer science , pattern recognition (psychology) , classifier (uml) , data mining , cross validation , artificial intelligence , mathematics , machine learning
Filter feature selection methods compute molecular signatures by selecting subsets of genes in the ranking of a valuation function. The motivations of the valuation functions choice are almost always clearly stated, but those for selecting the genes according to their ranking are hardly ever explicit.

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