Serotonin Syndrome with Escitolapram and Concomitant Use of Cocaine: A Case Report | Zendy

Hamood Ur-Rehman Malik | Zendy; Krishan Kumar | Zendy

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Serotonin Syndrome with Escitolapram and Concomitant Use of Cocaine: A Case Report

Author(s) -

Hamood Ur-Rehman Malik,

Krishan Kumar

Publication year - 2012

Publication title -

clinical medicine insights case reports

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.187

H-Index - 12

ISSN - 1179-5476

DOI - 10.4137/ccrep.s9540

Subject(s) - serotonin syndrome , medicine , serotonergic , neuroleptic malignant syndrome , lethargy , anesthesia , hyperreflexia , serotonin , hypertonia , concomitant , psychology , receptor

Serotonin syndrome is a potentially life-threatening condition caused by excessive serotonergic activity in the central nervous system. It is characterized by mental status changes (eg, confusion, agitation, lethargy, coma), autonomic instability (eg, hyperthermia, tachycardia, diaphoresis, nausea, vomiting, diarrhea, dilated pupils), and neuromuscular hyperactivity (eg, myoclonus, hyperreflexia, rigidity, trismus). Serotonin syndrome classically occurs in patients receiving two or more serotonergic drugs, but it can occur with monotherapy. We report a case of a 20-year-old man who developed serotonin syndrome resulting from overdose of Escitolapram with concomitant use of cocaine. It is a very important area in medicine as serotonin syndrome should be suspected especially in drug abusers who are being treated with psychotropic agents for mental illnesses.

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