A Case of Rheumatoid Arthritis with Bucillamine-Induced Yellow Nail Syndrome Initially Manifesting as Pulmonary Disease | Zendy

Takeo Isozaki | Zendy; Nobuyuki Yajima | Zendy; Michihito Sato | Zendy; Ryo Takahashi | Zendy; Kuninobu Wakabayashi | Zendy; Yusuke Miwa | Zendy; Masao Negishi | Zendy; Hirotsugu Ide | Zendy; Tsuyoshi Kasama | Zendy

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A Case of Rheumatoid Arthritis with Bucillamine-Induced Yellow Nail Syndrome Initially Manifesting as Pulmonary Disease

Author(s) -

Takeo Isozaki,

Nobuyuki Yajima,

Michihito Sato,

Ryo Takahashi,

Kuninobu Wakabayashi,

Yusuke Miwa,

Masao Negishi,

Hirotsugu Ide,

Tsuyoshi Kasama

Publication year - 2010

Publication title -

clinical medicine insights case reports

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.187

H-Index - 12

ISSN - 1179-5476

DOI - 10.4137/ccrep.s5514

Subject(s) - medicine , bronchiectasis , rheumatoid arthritis , dermatology , nail (fastener) , lymphedema , edema , arthritis , surgery , lung , materials science , cancer , breast cancer , metallurgy

We report a case of a 67-year-old woman with rheumatoid arthritis with yellow nail syndrome (YNS) that was caused by bucillamine. All three signs (yellow fingernails, lymphatic edema, and bronchiectasis) of YNS manifested, with characteristic timing, first with the nails turning yellow after when bronchiectasis was noticed. We reviewed 10 case reports from Japan and compared the periods until the appearance of yellow nails after starting bucillamine treatment, as well as those until lung disease and leg edema appeared.

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