Urinary Vitamin D-Binding Protein as a Biomarker of Steroid-Resistant Nephrotic Syndrome | Zendy

Michael Bennett | Zendy; Angad Pordal | Zendy; Christopher Haffner | Zendy; LaTawnya Pleasant | Zendy; Qing Ma | Zendy; Prasad Devarajan | Zendy

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Urinary Vitamin D-Binding Protein as a Biomarker of Steroid-Resistant Nephrotic Syndrome

Author(s) -

Michael Bennett,

Angad Pordal,

Christopher Haffner,

LaTawnya Pleasant,

Qing Ma,

Prasad Devarajan

Publication year - 2016

Publication title -

biomarker insights

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.075

H-Index - 31

ISSN - 1177-2719

DOI - 10.4137/bmi.s31633

Subject(s) - medicine , nephrotic syndrome , renal function , interquartile range , biomarker , creatinine , urinary system , urine , microalbuminuria , endocrinology , urology , gastroenterology , focal segmental glomerulosclerosis , nephrosis , proteinuria , kidney , chemistry , biochemistry

Idiopathic nephrotic syndrome (NS) is one of the most common glomerular disorders of childhood and is associated with increased urinary vitamin D-binding protein (uVDBP) excretion. We tested the hypothesis that uVDBP represents a biomarker to differentiate steroid-resistant nephrotic syndrome (SRNS) from the more benign forms of steroid-sensitive nephrotic syndrome (SSNS).

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