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Utility of C-terminal Telopeptide in Evaluating Levothyroxine Replacement Therapy-Induced Bone Loss
Author(s) -
Alap Christy,
Vivian D’Souza,
Ruby P. Babu,
Sohil Takodara,
Poornima Manjrekar,
Anupama Hegde,
M S Rukmini
Publication year - 2014
Publication title -
biomarker insights
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.075
H-Index - 31
ISSN - 1177-2719
DOI - 10.4137/bmi.s13965
Subject(s) - medicine , levothyroxine , n terminal telopeptide , bone remodeling , osteoporosis , euthyroid , bone mineral , bone resorption , type i collagen , endocrinology , urology , osteocalcin , hormone , biochemistry , chemistry , alkaline phosphatase , enzyme
Levothyroxine (LT4) therapy has shown to have effects on bone metabolism though its deleterious effect on bone remodeling is debatable. This study was aimed at assessing the diagnostic utility of the bone remodeling marker C-terminal telopeptide (CTx) in detecting early bone loss.

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