Clinico-Pathological Characteristics of Triple Negative and Non Triple Negative High Grade Breast Carcinomas with and without Basal Marker (CK5/6 and EGFR) Expression at a Rural Tertiary Hospital in India | Zendy

Chidambharam Choccalingam | Zendy; Lakshmi Rao | Zendy; Sruti Rao | Zendy

Open Access

Clinico-Pathological Characteristics of Triple Negative and Non Triple Negative High Grade Breast Carcinomas with and without Basal Marker (CK5/6 and EGFR) Expression at a Rural Tertiary Hospital in India

Author(s) -

Chidambharam Choccalingam,

Lakshmi Rao,

Sruti Rao

Publication year - 2012

Publication title -

breast cancer basic and clinical research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.741

H-Index - 23

ISSN - 1178-2234

DOI - 10.4137/bcbcr.s8611

Subject(s) - triple negative breast cancer , basal (medicine) , cytokeratin , immunohistochemistry , phenotype , pathology , breast cancer , breast carcinoma , biology , oncology , medicine , cancer , gene , biochemistry , insulin

Aims of the study were to evaluate the expression Cytokeratin 5/6(CK5/6) and Epidermal Growth Factor Receptor (EGFR) among triple negative breast cancers and high grade infiltrating duct carcinomas. Further to probe if triple negative phenotype can be a surrogate marker for basal phenotype and to correlate the expression of basal markers with disease free survivals among triple negative phenotype and high grade infiltrating duct carcinomas.

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