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The Efficacy of Intraoperative Frozen Section Analysis during Breast-Conserving Surgery for Patients with Ductal Carcinoma in Situ
Author(s) -
Mi Jin Kim,
Cheol Seung Kim,
Young Sam Park,
Eun Hye Choi,
Kyu Dam Han
Publication year - 2016
Publication title -
breast cancer basic and clinical research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.741
H-Index - 23
ISSN - 1178-2234
DOI - 10.4137/bcbcr.s40868
Subject(s) - ductal carcinoma , medicine , frozen section procedure , pathological , surgical margin , invasive ductal carcinoma , malignancy , incidence (geometry) , radiology , breast cancer , breast surgery , resection , surgery , cancer , physics , optics
Recently, the incidence of ductal carcinoma in situ (DCIS), a noninvasive breast malignancy, has increased. This has resulted in an increase in the incidence of breast-conserving surgery (BCS). Numerous studies have suggested that intraoperative frozen section analysis (IFSA) could reduce the rate of additional excisions required to obtain adequate resection margins. However, DCIS is a known risk factor for positive margin status during BCS. Furthermore, some authors have concluded that IFSA may not be reliable for the detection of DCIS.

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