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Effect of scaling and root planing on levels of 8-hydroxydeoxyguanosine in gingival crevicular fluid of chronic periodontitis patients with and without Type II diabetes mellitus
Author(s) -
Maria Subash Aaron Muthuraj,
Srihari Janakiram,
Koshy Chithresan,
Arun Maradi,
Praveen Krishna Maddur,
Rajesh Rangaraju
Publication year - 2017
Publication title -
journal of indian society of periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.309
H-Index - 28
eISSN - 0975-1580
pISSN - 0972-124X
DOI - 10.4103/jisp.jisp_184_17
Subject(s) - medicine , scaling and root planing , chronic periodontitis , gastroenterology , diabetes mellitus , type 2 diabetes mellitus , periodontitis , periodontium , bleeding on probing , hemoglobin , type 2 diabetes , glycated hemoglobin , clinical attachment loss , dentistry , mann–whitney u test , endocrinology
Chronic periodontitis (CP) and diabetes mellitus are associated with increased oxidative damage to DNA with formation of 8-hydroxydeoxyguanosine (8-OHdG). The aim of this study was to evaluate the change in gingival crevicular fluid (GCF) levels of 8-OHdG and glycosylated hemoglobin (HbA1c) by 3 months after scaling and root planing (SRP), in CP patients with and without Type II diabetes mellitus.

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