Prostate cancer risk prediction models in Eastern Asian populations: current status, racial difference, and future directions | Zendy

Xu Gao | Zendy; Yinghao Sun | Zendy; Biming He | Zendy; Rui Chen | Zendy; Tianqi Sun | Zendy; Yue Yang | Zendy; Chun-Lei Zhang | Zendy; Shancheng Ren | Zendy

Open Access

Prostate cancer risk prediction models in Eastern Asian populations: current status, racial difference, and future directions

Author(s) -

Xu Gao,

Yinghao Sun,

Biming He,

Rui Chen,

Tianqi Sun,

Yue Yang,

Chun-Lei Zhang,

Shancheng Ren

Publication year - 2019

Publication title -

asian journal of andrology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.701

H-Index - 74

eISSN - 1745-7262

pISSN - 1008-682X

DOI - 10.4103/aja.aja_55_19

Subject(s) - prostate cancer , medicine , oncology , population , prostate specific antigen , demography , cancer , gynecology , environmental health , sociology

Prostate cancer (PCa) risk calculators (RCs) with prostate-specific antigen (PSA) and other risk factors can greatly improve the accurate prediction of potential risk of PCa compared to PSA. The European Randomized Study of Screening for PCa Risk Calculator (ERSPC-RC) and the Prostate Cancer Prevention Trial Risk Calculator (PCPT-RC) are developed on the Western population. However, the Western RCs showed limited diagnostic efficacy in the Eastern Asian population, mainly due to racial differences between the two populations. We aimed to review the application of Western RCs and Eastern Asian RCs in Eastern Asian cohorts and to identify the characteristics and efficacy of these RCs.

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