Open AccessTakotsubo Cardiomyopathy after Treatment of Pulmonary Arterial Hypertension
Author(s) -
Cork David P.,
Mehrotra Amit K.,
GombergMaitland Mardi
Publication year - 2012
Publication title -
pulmonary circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.791
H-Index - 40
ISSN - 2045-8940
DOI - 10.4103/2045-8932.101659
Subject(s) - medicine , cardiomyopathy , treprostinil , cardiology , pulmonary hypertension , complication , disease , cardiac function curve , emotional stress , heart failure
Pulmonary arterial hypertension is a fatal disease. Intravenous prostanoids are often utilized for long‐term management of patients. The therapy requires a significant commitment and change in lifestyle for both the patient and family. Takotsubo cardiomyopathy, transient apical ballooning syndrome, has been reported in association with emotional and physical stress. This case report describes a patient with pulmonary arterial hypertension who developed Takotsubo cardiomyopathy after treatment initiation with intravenous treprostinil. Over time, the syndrome resolved and the patient had return of normal left ventricular function. Takotsubo cardiomyopathy should be recognized as a potential, rare complication of therapy initiation due to the severity of the illness and the emotional stress of the disease.