The impact of Zika virus infection on human neuroblastoma (SH-SY5Y) cell line | Zendy

Natthanej Luplertlop | Zendy; San Suwanmanee | Zendy; Watcharamat Muangkaew | Zendy; Sumate Ampawong | Zendy; Thitinan Kitisin | Zendy; Yong Poovorawan | Zendy

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The impact of Zika virus infection on human neuroblastoma (SH-SY5Y) cell line

Author(s) -

Natthanej Luplertlop,

San Suwanmanee,

Watcharamat Muangkaew,

Sumate Ampawong,

Thitinan Kitisin,

Yong Poovorawan

Publication year - 2017

Publication title -

journal of vector borne diseases

Language(s) - English

Resource type - Journals

ISSN - 0972-9062

DOI - 10.4103/0972-9062.217611

Subject(s) - sh sy5y , virology , vero cell , zika virus , biology , cell culture , in vitro , virus , cell , neuroblastoma , biochemistry , genetics

An increase in Zika virus (ZIKV) epidemic during the last decade has become a major global concern as the virus affects both newborns and adult humans. Earlier studies have shown the impact of ZIKV infection in developing human foetus. However, effective in vitro model of target cells for studying the ZIKV infection in adult human neurons is not available. This study aimed to establish the use of human neuroblastoma cell line (SH-SY5Y) for studying an infection of ZIKV in vitro.

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