Analysis of matrix metalloproteinase-8 levels in gingival crevicular fluid and whole mouth fluid among smokers and nonsmokers using enzyme-linked immune-sorbent assay and a novel chair-side test | Zendy

Ghousia Akbari | Zendy; Munivenkatappa Lakshmaiah Venkatesh Prabhuji | Zendy; Bangalore Vardhan Karthikeyan | Zendy; Kanugondappa Raghunatha | Zendy; Roopalakshmi Narayanan | Zendy

Open Access

Analysis of matrix metalloproteinase-8 levels in gingival crevicular fluid and whole mouth fluid among smokers and nonsmokers using enzyme-linked immune-sorbent assay and a novel chair-side test

Author(s) -

Ghousia Akbari,

Munivenkatappa Lakshmaiah Venkatesh Prabhuji,

Bangalore Vardhan Karthikeyan,

Kanugondappa Raghunatha,

Roopalakshmi Narayanan

Publication year - 2015

Publication title -

journal of indian society of periodontology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.309

H-Index - 28

eISSN - 0975-1580

pISSN - 0972-124X

DOI - 10.4103/0972-124x.162201

Subject(s) - medicine , periodontium , chronic periodontitis , saliva , gingivitis , periodontitis , gastroenterology , dentistry , population , environmental health

To indigenously prepare a chair-side test kit for investigating and comparing the matrix metalloproteinase (MMP)-8 levels in gingival crevicular fluid (GCF) and saliva in patients with healthy periodontium, gingivitis and chronic periodontitis in smokers and nonsmokers. To validate the diagnostic accuracy of indigenously prepared chair-side test against enzyme-linked immune-sorbent assay (ELISA). Furthermore, to assess the effect of nonsurgical periodontal therapy (NSPT) on the levels of MMP-8 in GCF and saliva among the test groups.

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