Pharmacogenomic association study on the role of drug metabolizing, drug transporters and drug target gene polymorphisms in drug-resistant epilepsy in a north Indian population | Zendy

Ritu Kumari | Zendy; Ram Lakhan | Zendy; Ravindra Kumar Garg | Zendy; Jayantee Kalita | Zendy; U. K. Misra | Zendy; Balraj Mittal | Zendy

Open Access

Pharmacogenomic association study on the role of drug metabolizing, drug transporters and drug target gene polymorphisms in drug-resistant epilepsy in a north Indian population

Author(s) -

Ritu Kumari,

Ram Lakhan,

Ravindra Kumar Garg,

Jayantee Kalita,

U. K. Misra,

Balraj Mittal

Publication year - 2011

Publication title -

indian journal of human genetics

Language(s) - English

Resource type - Journals

eISSN - 0971-6866

pISSN - 1998-362X

DOI - 10.4103/0971-6866.80357

Subject(s) - pharmacogenetics , genotyping , pharmacogenomics , genotype , odds ratio , cyp2c9 , epilepsy , drug , medicine , pharmacology , biology , polymorphism (computer science) , genetics , gene , psychiatry

In epilepsy, in spite of the best possible medications and treatment protocols, approximately one-third of the patients do not respond adequately to anti-epileptic drugs. Such interindividual variations in drug response are believed to result from genetic variations in candidate genes belonging to multiple pathways.

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