Poorly differentiated (insular) thyroid carcinoma arising in a long-standing colloid goitre: A cytological dilemma | Zendy

Hema Kini | Zendy; M Nirupama | Zendy; AarathiR Rau | Zendy; Sumit Gupta | Zendy; Alfred J. Augustine | Zendy

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Poorly differentiated (insular) thyroid carcinoma arising in a long-standing colloid goitre: A cytological dilemma

Author(s) -

Hema Kini,

M Nirupama,

AarathiR Rau,

Sumit Gupta,

Alfred J. Augustine

Publication year - 2012

Publication title -

journal of cytology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.267

H-Index - 19

eISSN - 0974-5165

pISSN - 0970-9371

DOI - 10.4103/0970-9371.93237

Subject(s) - medicine , thyroglobulin , thyroid , thyroid neoplasm , pathology , follicular carcinoma , neoplasm , thyroid carcinoma , follicular phase , goiter , carcinoma , anaplastic carcinoma , papillary carcinoma

Poorly differentiated (insular) thyroid carcinoma (PDITC) is an uncommon thyroglobulin producing neoplasm intermediate in aggressiveness between well-differentiated carcinomas of follicular cell origin and undifferentiated anaplastic carcinoma. Its cytomorphological recognition is essential for planning surgery and subsequent management as it is known for its aggressive behavior, advanced stage at presentation, local recurrences and rapid dissemination. We report a case of PDITC arising in a long-standing goiter, in which presence of microfollicular structures and minimal necrosis resulted in difficulty in distinguishing it from a follicular neoplasm of thyroid.

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