Hyaluronic acid: A promising mediator for periodontal regeneration | Zendy

Suresh Kedige | Zendy; Jyoti Bansal | Zendy; Samir Anand | Zendy

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Hyaluronic acid: A promising mediator for periodontal regeneration

Author(s) -

Suresh Kedige,

Jyoti Bansal,

Samir Anand

Publication year - 2010

Publication title -

indian journal of dental research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.277

H-Index - 43

eISSN - 1998-3603

pISSN - 0970-9290

DOI - 10.4103/0970-9290.74232

Subject(s) - hyaluronic acid , regeneration (biology) , periodontitis , wound healing , glycosaminoglycan , extracellular matrix , gingivitis , medicine , dentistry , mediator , periodontal disease , chemistry , immunology , microbiology and biotechnology , biology , anatomy , biochemistry

Hyaluronic acid (HA) is a natural-non sulphated high molecular weight glycosaminoglycan that forms a critical component of the extracellular matrix and contributes significantly to tissue hydrodynamics, cell migration and proliferation. The use of HA in the treatment of inflammatory process is established in medical areas such as orthopedics, dermatology and ophthalmology. In the field of dentistry, hyaluronate has shown anti-inflammatory, antiedematous and anti-bacterial effects for the treatment of gingivitis and periodontitis. Due to its potential role in modulation of wound healing, its administration to periodontal wound sites could achieve comparable beneficial effects in periodontal tissue regeneration and periodontal disease treatment.

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