Principles of gene therapy | Zendy

Biju Mammen | Zendy; T Ramakrishnan | Zendy; Uma Sudhakar | Zendy; Vijayalakshmi | Zendy

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Principles of gene therapy

Author(s) -

Biju Mammen,

T Ramakrishnan,

Uma Sudhakar,

Vijayalakshmi

Publication year - 2007

Publication title -

indian journal of dental research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.277

H-Index - 43

eISSN - 1998-3603

pISSN - 0970-9290

DOI - 10.4103/0970-9290.35832

Subject(s) - gene , genetic enhancement , computational biology , encode , periodontology , genetics , biology , bioinformatics , medicine , dentistry

Genes are specific sequences of bases that encode instructions to make proteins. When genes are altered so that encoded proteins are unable to carry out their normal functions, genetic disorders can result. Gene therapy is designed to introduce genetic material into cells to compensate for abnormal genes or to make a beneficial protein. This article reviews the fundamentals in gene therapy and its various modes of administration with an insight into the role of gene therapy in Periodontics and future percepts and the technical and ethical issues of using gene therapy.

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