Open AccessLymphoepithelioma-like carcinoma of the urinary bladder: report of a rare case
Author(s) -
Naorem Gopendro Singh,
Abul Ala Syed Rifat Mannan,
Amre A. Rifaat,
Mirza Kahvic
Publication year - 2009
Publication title -
annals of saudi medicine/annals of saudi medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.373
H-Index - 44
eISSN - 0975-4466
pISSN - 0256-4947
DOI - 10.4103/0256-4947.57173
Subject(s) - medicine , lymphoepithelioma like carcinoma , urinary bladder , urology , carcinoma , urinary system , pathology , virus , virology , epstein–barr virus
Lymphoepithelioma-like carcinoma (LELC) is a rare malignant neoplasm in the urinary bladder, which can histologically mimic lymphoma, poorly differentiated invasive transitional cell carcinoma or poorly differentiated squamous cell carcinoma with a lymphoplasmacytic background. A urinary bladder tumor was identified in a 65-year-old man suffering from hematuria for several weeks. Transurethral biopsy revealed an undifferentiated tumor with prominent lymphocytes and plasma cell infiltration. Immunohistochemical evaluation showed positive staining for cytokeratin and epithelial membrane antigen. Subsequent radical cystectomy showed pure LELC. We present the case to highlight the significance of recognizing this unusual bladder tumor and discuss the important differential diagnosis, treatment options and prognosis.