Detection of Amp C genes encoding for beta-lactamases in Escherichia coli and Klebsiella pneumoniae | Zendy

Shanthi Mariappan | Zendy; Uma Sekar | Zendy; Kavita Arunagiri | Zendy; Balaraman Sekar | Zendy

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Detection of Amp C genes encoding for beta-lactamases in Escherichia coli and Klebsiella pneumoniae

Author(s) -

Shanthi Mariappan,

Uma Sekar,

Kavita Arunagiri,

Balaraman Sekar

Publication year - 2012

Publication title -

indian journal of medical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.382

H-Index - 48

eISSN - 1998-3646

pISSN - 0255-0857

DOI - 10.4103/0255-0857.99489

Subject(s) - cefoxitin , klebsiella pneumoniae , microbiology and biotechnology , imipenem , enterobacter cloacae , cephalosporin , broth microdilution , meropenem , beta lactamase , escherichia coli , biology , multiplex polymerase chain reaction , citrobacter freundii , antibiotics , antibiotic resistance , minimum inhibitory concentration , polymerase chain reaction , bacteria , gene , genetics , staphylococcus aureus

Amp C beta-lactamase are Ambler class C enzymes that confer resistance to extended spectrum cephalosporins and are not inhibited by beta-lactamase inhibitors. Their detection is crucial, since the phenotypic tests are not standardised leading to ambiguity in interpretation of results. This study was done to detect the types of Amp C prevalent in Escherichia coli and Klebsiella pneumoniae by multiplex polymerase chain reaction (PCR).

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