Open AccessEffect of aqueous extract of Achillea millefolium on the development of experimental autoimmune encephalomyelitis in C57BL/6 mice
Author(s) -
Reza Vazirinejad,
Fateme Ayoobi,
Mohammad Kazemi Arababadi,
Mohammad Mahdi Eftekharian,
Ali Darekordi,
Mahdi Goudarzvand,
Gholamhossein Hassanshahi,
Mohammad Mohsen Taghavi,
Behzad Nasiri Ahmadabadi,
Derek Kennedy,
Ali Shamsizadeh
Publication year - 2014
Publication title -
indian journal of pharmacology/the indian journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.286
H-Index - 59
eISSN - 1998-3751
pISSN - 0253-7613
DOI - 10.4103/0253-7613.132168
Subject(s) - achillea millefolium , experimental autoimmune encephalomyelitis , luxol fast blue stain , h&e stain , medicine , immunology , encephalomyelitis , cytokine , pharmacology , multiple sclerosis , endocrinology , traditional medicine , myelin , central nervous system , immunohistochemistry
Achillea millefolium (A. millefolium) is widely used as an anti-inflammatory remedy in traditional and herbal medicine. In this study, we investigated the effect of an aqueous extract from A. millefolium on experimental autoimmune encephalomyelitis (EAE) and on the serum cytokine levels in C57BL/6 mice.