Open AccessSynthesis, Characterization and Biocidal Activities of Some Schiff Base Metal Complexes
Author(s) -
M.A. Neelakantan,
M Esakkiammal,
S.S. Mariappan,
Jeyaprakash Dharmaraja,
Thayalaraj Christopher Jeyakumar
Publication year - 2010
Publication title -
indian journal of pharmaceutical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.245
H-Index - 57
eISSN - 1998-3743
pISSN - 0250-474X
DOI - 10.4103/0250-474x.65015
Subject(s) - schiff base , chemistry , metal , ligand (biochemistry) , sulfonamide , proton nmr , elemental analysis , stereochemistry , polymer chemistry , medicinal chemistry , yeast , phenanthroline , nuclear chemistry , organic chemistry , biochemistry , receptor
Some new mixed ligand complexes (1-5) of type ML'B (M(II)=Mn(II), Co(II), Ni(II), Cu(II) and Zn(II); HL'= o-vanillidene-2-aminobenzothiazole; B= 1,10-phenanthroline) and Schiff base metal complexes of types (ML(2)") (6-10) and (M(2)L") (11-15) (HL"= o-vanillidene-2-amino-N-(2-pyridyl)-benzene sulfonamide) were synthesized and characterized by elemental analysis and spectral (IR, (1)H NMR and (13)C NMR) studies. The free ligands and their metal complexes have been screened for their in vitro biological activities against bacteria, fungi and yeast. The metal complexes show more potent activities compared with Schiff base ligands.
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