CARDIOVASCULAR RISK IN ESSENTIAL THROMBOCYTHEMIA AND POLYCYTHEMIA VERA: THROMBOTIC RISK AND SURVIVAL
Author(s) -
Vincenzo Accurso,
Marco Santoro,
Salvatrice Mancuso,
Angelo Davide Contrino,
Paolo Casimio,
Mariano Sardo,
Simona Raso,
F. Di Piazza,
Alessandro Perez,
Marco Bono,
Antonio Russo,
Sergio Siragusa
Publication year - 2020
Publication title -
mediterranean journal of hematology and infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.682
H-Index - 31
ISSN - 2035-3006
DOI - 10.4084/mjhid.2020.008
Subject(s) - essential thrombocythemia , medicine , polycythemia vera , dyslipidemia , diabetes mellitus , thrombosis , platelet , myelofibrosis , gastroenterology , obesity , cardiology , endocrinology , bone marrow
Thromboembolic and bleeding events pose a severe risk for patients with Polycythemia Vera (PV) and Essential Thrombocythemia (ET). Many factors can contribute to promoting the thrombotic event due to the interaction between platelets, leukocytes, and endothelium alterations. Moreover, a significant role can be played by cardiovascular risk factors (CV.R) such as cigarette smoking habits, hypertension, diabetes, obesity and dyslipidemia. In this study, we evaluated the impact that CV.R plays on thrombotic risk and survival in patients with PV and ET.
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