Open AccessVIRAL LOAD AND NUCLEOTIDE SUBSTITUTIONS IN HEPATITIS B VIRUSES DERIVED FROM CHRONIC HBV PATIENTS
Author(s) -
Narjes Shokatpour,
Maryam Vaezjalali,
Graham R. Foster,
Shahnaz Sali
Publication year - 2019
Publication title -
mediterranean journal of hematology and infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.682
H-Index - 31
ISSN - 2035-3006
DOI - 10.4084/mjhid.2019.046
Subject(s) - hbsag , hepatitis b virus , virology , mutation , medicine , epitope , gene , hepatitis b , mutant , viral load , virus , antibody , biology , genetics , immunology
Our results showed common mutations within HBsAg, occurring in immune epitopes, a high rate of G1896A mutations in the PC region, and a negative correlation between the emergence of A1762T/G1764A mutation and the G1764T/C1766G mutant in the BCP region.
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