Increase in Candida parapsilosis candidemia in cancer patients

This study aimed to identify the risk factors of candidemia and asses possible clinically significant differences between and other in a Chinese tertiary cancer center over six years. A total of 323 cancer patients were enrolled and analyzed from 2012 to 2018. Among the isolates, the species most frequently isolated was (37.15%, 120/323), and only accounted for 34.37%. Based on statistical analysis, when candidemia patients who had were compared with other ., the following factors were found to be significantly associated with fungemia: parenteral nutrition (p < 0.001), neutropenia (p < 0.001), receipt of chemotherapy (p = 0.002), and previous antifungal use (p < 0.001). Parenteral nutrition was a factor that independently predicted candidemia (OR, 0.183; 95% CI, 0.098-0.340; p < 0.001).In short, as the leading non-albicans . isolates in candidemia are posing a major threat for cancer patients. The study highlights the urgent need to evaluate the possibility of development of candidemia in cancer patients exposed to these risk factors effective and prevention strategies against this causative agent transmitted through nosocomial route should be implemented.