THE USE OF HPLC AS A TOOL FOR NEONATAL CORD BLOOD SCREENING OF HAEMOGLOBINOPATHY - A VALIDATION STUDY | Zendy

Ali AlMadhani | Zendy; Anil Pathare | Zendy; Salam Alkindi | Zendy

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THE USE OF HPLC AS A TOOL FOR NEONATAL CORD BLOOD SCREENING OF HAEMOGLOBINOPATHY - A VALIDATION STUDY

Author(s) -

Ali AlMadhani,

Anil Pathare,

Salam Alkindi

Publication year - 2019

Publication title -

mediterranean journal of hematology and infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.682

H-Index - 31

ISSN - 2035-3006

DOI - 10.4084/mjhid.2019.005

Subject(s) - medicine , cord blood , cohort , newborn screening , thalassemia , pediatrics , hemoglobin , cohort study , anemia , fetal hemoglobin , hemoglobinopathy , obstetrics , hemolytic anemia , pregnancy , fetus , genetics , biology

The study validated the earlier observation by 100% concordance with the results of CBC and HPLC. Presence of Hb Bart's at birth does not always mean the presence of alpha thalassemia, as subjects with Hb Bart's below 1% by quantitation, were shown to be normal by molecular studies.

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