Cherubism in Sub-Saharan Africa: A First Case-Report in a Child
Author(s) -
Michel Ntetani Aloni,
Renault Sitwaminya Kambere,
Antoine Molua,
Joseph Nzinga Dilu,
Pierre M. Tshibassu,
Aimé Kazadi Lukusa,
René Makuala Ngiyulu,
Raphael Mbona Kalengayi,
Jean Lambert Gini Ehungu
Publication year - 2015
Publication title -
rare tumors
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.285
H-Index - 15
eISSN - 2036-3613
pISSN - 2036-3605
DOI - 10.4081/rt.2015.5675
Subject(s) - cherubism , medicine , giant cell , physical examination , pathology , population , connective tissue , dermatology , radiology , environmental health
Cherubism is rare disease and has been rarely reported in African pediatric population. We report here the case of a 10-year-old child who was referred to our hospital for bilateral jaws swelling. Physical examination revealed bilateral swelling symmetry of the face. Histopathological examination of the biopsy specimen showed loose fibrous stroma, proliferating fibrous connective with tissue interspersed with multinucleated giant cells, small thin walled blood vessels and scattered sparse mononuclear inflammatory infiltrate. Our patient presented cherubism. Cherubism is rarely described in children living in sub-Saharan Africa. Genetic and molecular investigations plays an important role in diagnosis but were not available in poor resources settings in developing countries such as the Democratic Republic of Congo
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