Prostatic Stromal Sarcoma in an Adolescent: The Role of Chemotherapy
Author(s) -
Elena Cavaliere,
Rita Alaggio,
Marco Castagnetti,
Giovanni Scarzello,
Gianni Bisogno
Publication year - 2014
Publication title -
rare tumors
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.285
H-Index - 15
eISSN - 2036-3613
pISSN - 2036-3605
DOI - 10.4081/rt.2014.5607
Subject(s) - medicine , chemotherapy , ifosfamide , vincristine , doxorubicin , sarcoma , stromal tumor , oncology , stromal cell , pathology , cyclophosphamide , cisplatin
Prostatic stromal sarcoma (PSS) is a rare tumor that normally occurs in adult age. Its management relies mainly on surgery. We report the first case of PSS occurring in an adolescent. There was evidence of a good response to chemotherapy including ifosfamide, doxorubicin, vincristine and actinomycin-D, although the final outcome was dismal. A review of the English literature revealed 14 additional patients with PSS treated with chemotherapy: tumor shrinkage was reported in 4 of the 6 evaluable patients. Patients with PSS may benefit from the use of chemotherapy in combination with early aggressive local treatment
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