A Case of Small Cell Carcinoma of the Vagina | Zendy

Ryosuke Tamura | Zendy; Yoshihito Yokoyama | Zendy; Asami Kobayashi | Zendy; Yuuki Osawa | Zendy; Tatsuhiko Shigeto | Zendy; Masayuki Futagami | Zendy; Hideki Mizunuma | Zendy

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A Case of Small Cell Carcinoma of the Vagina

Author(s) -

Ryosuke Tamura,

Yoshihito Yokoyama,

Asami Kobayashi,

Yuuki Osawa,

Tatsuhiko Shigeto,

Masayuki Futagami,

Hideki Mizunuma

Publication year - 2013

Publication title -

rare tumors

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.285

H-Index - 15

eISSN - 2036-3613

pISSN - 2036-3605

DOI - 10.4081/rt.2013.e58

Subject(s) - medicine , vagina , external beam radiotherapy , chromogranin a , radiation therapy , cervix , small cell carcinoma , carcinoma , pathology , radiology , surgery , cancer , brachytherapy , immunohistochemistry

Primary small cell carcinoma of the vagina is quite rare, and a standard treatment has not been established yet. Herein, we report a case of an 81-year-old woman who was diagnosed with a vaginal tumor without continuity with the uterine cervix. Histopathological diagnosis indicated alveolar solid growth of nuclear chromatin-rich atypical cells with a high N/C ratio and a partially recognized rosette-like structure, suggesting a differentiated neuroendocrine system. Chromogranin A and synapto- physin were positive. Stage I vaginal small cell carcinoma localized to the vagina was diagnosed. The tumor disappeared by radiation monotherapy with external beam irradiation and endocavitary irradiation. The patient remains alive without any disease 1 year and 8 months after the treatment, suggesting the efficacy of radiotherapy in small cell carcinoma of the vagina.

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