A Very Unusual Thyroid Tumor: A Nodule with Mature Fat Papillary Hyperplasia and Focal Atypia
Author(s) -
Claudio Cacchi,
H Arnholdt,
Armando Bartolazzi
Publication year - 2013
Publication title -
rare tumors
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.285
H-Index - 15
eISSN - 2036-3613
pISSN - 2036-3605
DOI - 10.4081/rt.2013.e50
Subject(s) - medicine , atypia , pathology , nodule (geology) , thyroid , pathological , hyperplasia , lesion , thyroid carcinoma , goiter , paleontology , biology
Fat-containing lesions of the thyroid are rare, encompassing several clinical-pathological conditions such adenolipomas, thyrolipomatosis and lipomotous tissue in case of amyloidosis. Furthermore, cases of papillary thyroid carcinoma have been identified in association with thyrolipomatosis. We report a case of 51 years old man referred to surgery for a multinodular goiter, showing multiple cystic and hemorrhagic nodules of up to 3 cm. One of these lesions showed features of papillary hyperplasia with focal cytological atypia and mature fat. Here, we describe and discuss the histological and immunophenotypical features of this rare lesion
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