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Lung carcinoma with hypertrophic osteoarthropathy in a teenager
Author(s) -
Rowan Miller,
Rowland Illing,
Jeremy Whelan
Publication year - 2011
Publication title -
rare tumors
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.285
H-Index - 15
eISSN - 2036-3613
pISSN - 2036-3605
DOI - 10.4081/rt.2011.e8
Subject(s) - medicine , hypertrophic osteoarthropathy , malignancy , lung , lung cancer , disease , adenocarcinoma , pathology , cystic fibrosis , spinal osteoarthropathy , cancer , dermatology
Hypertrophic osteoarthropathy (HOA) characterised by arthralgia, clubbing and periosteal proliferation of long bones, is rarely encountered in children and adolescents. Whereas in adults over 80% of cases are associated with malignancy, in children the majority of cases are due to non-neoplastic causes such as cystic fibrosis, bilary atresia and congenital heart disease. Up to 5% of adults with lung cancer demonstrate signs of HOA. However, lung cancer is extremely uncommon in children and young people. Here we report a case of lung adenocarcinoma in an 18 year old male associated with HOA present both at diagnosis and at subsequent disease progression

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