Merkel cell tumor of the skin treated with localized radiotherapy: are widely negative margins required?
Author(s) -
Mark Trombetta,
Matthew Packard,
Claudia Velosa,
Jan F. Silverman,
Day Werts,
David S. Parda
Publication year - 2011
Publication title -
rare tumors
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.285
H-Index - 15
eISSN - 2036-3613
pISSN - 2036-3605
DOI - 10.4081/rt.2011.e12
Subject(s) - medicine , merkel cell carcinoma , radiation therapy , adjuvant radiotherapy , wide local excision , merkel cell , natural history , distant metastasis , surgical excision , dermatology , metastasis , skin tumor , surgery , pathology , carcinoma , cancer , carcinogenesis
Merkel’s cell carcinoma is a rare cutaneous tumor that can affect a wide variety of sites throughout the body. Commonly, it affects the skin alone and the management of limited disease can be confusing since the natural history of the disease involves distant metastasis. Traditional management has required wide local excision with negative margins of resection. We describe a case treated with local therapy alone and review the literature to suggest that complete microscopic excision may not be required if adjuvant radiotherapy is used
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom