Does intravenous administration of recombinant tissue plasminogen activator for ischemic stroke can cause inferior myocardial infarction? | Zendy

Mostafa AlmasiDooghaee | Zendy; Saeed Razmeh | Zendy; Amir Hassan Habibi | Zendy; Amir Hassan Rezaee | Zendy

Open Access

Does intravenous administration of recombinant tissue plasminogen activator for ischemic stroke can cause inferior myocardial infarction?

Author(s) -

Mostafa AlmasiDooghaee,

Saeed Razmeh,

Amir Hassan Habibi,

Amir Hassan Rezaee

Publication year - 2016

Publication title -

neurology international

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.39

H-Index - 16

ISSN - 2035-8377

DOI - 10.4081/ni.2016.6617

Subject(s) - medicine , myocardial infarction , chest pain , percutaneous coronary intervention , tissue plasminogen activator , cardiology , stroke (engine) , complication , artery , recombinant tissue plasminogen activator , anesthesia , surgery , ischemia , ischemic stroke , mechanical engineering , modified rankin scale , engineering

Recombinant tissue plasminogen activator (rTPA) is one of the main portions of acute ischemic stroke management, but unfortunately has some complications. Myocardial infarction (MI) is a hazardous complication of administration of intravenous rTPA that has been reported recently. A 78-year-old lady was admitted for elective coronary artery bypass graft surgery. On the second day of admission, she developed acute left hemiparesis and intravenous rTPA was administered within 120 minutes. Three hours later, she has had chest pain. Rescue percutaneous coronary intervention was performed on right coronary artery due to diagnosis of inferior MI, and the symptoms were resolved

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