Mean platelet volume as diagnostic and therapeutic marker of risk and prognosis of heart disease | Zendy

Henshaw Uchechi Okoroiwu | Zendy; Christopher Ogar Ogar | Zendy

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Mean platelet volume as diagnostic and therapeutic marker of risk and prognosis of heart disease

Author(s) -

Henshaw Uchechi Okoroiwu,

Christopher Ogar Ogar

Publication year - 2018

Publication title -

italian journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.134

H-Index - 10

eISSN - 1877-9352

pISSN - 1877-9344

DOI - 10.4081/itjm.2018.918

Subject(s) - medicine , mean platelet volume , cardiology , biomarker , atrial fibrillation , stroke (engine) , coronary artery disease , platelet , platelet activation , mechanical engineering , biochemistry , chemistry , engineering

Increased mean platelet volume (MPV) is associated with platelet reactivity and is a predictor of cardiovascular risk and unprovoked nervous thromboembolism. Mean platelet volume is a precise measure of platelet size. Studies have reported the use of MPV as a biomarker for predicting ischemic stroke in atrial fibrillation patients as well as in anticoagulant prescription and rhythm-control therapy. Moreover, MPV may predict cardiovascular event outcome following percutaneous coronary intervention in patients with coronary artery disease. MPV may predict residual platelet reactivity in dual antiplatelet therapy. Factors influencing MPV result were discussed. This review centered on the reports that MPV may be a biomarker of risk and prognosis of prevalent heart diseases.

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