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CD30+ primary cutaneous post-transplant lymphoproliferative disorder with signet-ring cell features
Author(s) -
Neeta Malviya,
Heather Wickless
Publication year - 2016
Publication title -
hematology reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.239
H-Index - 12
ISSN - 2038-8330
DOI - 10.4081/hr.2016.6433
Subject(s) - cd30 , medicine , post transplant lymphoproliferative disorder , lymphomatoid papulosis , lymphoproliferative disorders , signet ring cell , pathology , viremia , epstein–barr virus , in situ hybridization , virus , immunology , immunohistochemistry , lymphoma , cancer , biology , adenocarcinoma , biochemistry , gene expression , gene
We report a case of primary cutaneous CD30+ post-transplant lymphoproliferative disorder with an uncommon finding of signet ring cell features in a heart transplant patient. The neoplastic cells were CD4 and CD30 positive, and negative for S-100, pancytokeratin, myeloperoxidase, and CD56. In situ hybridization for Epstein Barr Virus (EBV) was negative, even though the patient did have EBV viremia

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